Research into Peptides
Your direct source for raw data, clinical breakdowns, and industry updates on the frontier of peptide science.
*For research purposes only - not for human consumption*
Recovery & Repair Research
Pharmacological Activation of the AMPK Pathway as a Driver of Adaptive Mitochondrial Biogenesis and Endurance Performance
This is the landmark study that made AICAR famous worldwide, earning it the nickname "exercise in a pill."
Muscle Performance and Enhanced Recovery (5-Amino-1MQ)
This study evaluated how the compound impacts aging muscle and exercise dynamics.
Biomarker Correlation in Obesity and Insulin Resistance (Observational)
This trial analysed how metabolic dysfunction impacts baseline circulating MOTS-c levels in human adults.
Body Composition Research
Pharmacological Activation of the AMPK Pathway as a Driver of Adaptive Mitochondrial Biogenesis and Endurance Performance
This is the landmark study that made AICAR famous worldwide, earning it the nickname "exercise in a pill."
Muscle Performance and Enhanced Recovery (5-Amino-1MQ)
This study evaluated how the compound impacts aging muscle and exercise dynamics.
Biomarker Correlation in Obesity and Insulin Resistance (Observational)
This trial analysed how metabolic dysfunction impacts baseline circulating MOTS-c levels in human adults.
Hormone Vitality Research
Characterization of the Potent Growth Hormone-Releasing Activity of Hexarelin in Human Subjects: A Comparative Endocrine Evaluation
This foundational clinical study evaluated the direct potency of Hexarelin in comparison to native Growth Hormone-Releasing Hormone (GHRH), establishing its place as an elite-tier secretagogue.
The Phase 3 Clinical Trial for Visceral Fat Atrophy with Tesamorelin.
This landmark multi-center human trial evaluated Tesamorelin's ability to selectively eliminate dangerous, deep-belly fat (visceral adipose tissue) and reverse severe metabolic complications.
Pulsatile Secretion Kinetics and Endocrine Integrity Maintenance Following Intravenous and Subcutaneous Administration of Growth Hormone-Releasing Factor (GRF 1-29) in Human Subjects
This landmark clinical human study maps out how Sermorelin stimulates growth hormone release while cleanly preserving the natural physiological peaks and valleys of the endocrine system.
Growth & Performance Research
Prolonged Stimulation of Pulsatile Growth Hormone Secretion via Therapeutic Affinity Complexation of GHRH Analogs in Human Subjects
CJC-1295 is a synthetic analog of Growth Hormone-Releasing Hormone (GHRH). In the literature, its evaluation centers on the addition of DAC (Drug Affinity Complex), which binds to blood proteins to turn a short-lived signal into a long-lasting compound.
The Impact of PEGylation on Half-Life and Anabolic Stability
This foundational pharmacokinetic study established how attaching a PEG molecule alters the survival time and performance of MGF in biological systems.
Local Hypertrophy and Rapid Skeletal Muscle Mass Atrophy Reversal with MGF
This study evaluated the direct anabolic potency of local MGF administration in skeletal muscle tissue independently of systemic growth hormone levels.
Longevity Research
Late-Life Functional Restoration and Frailty Reversal with SS-31
This study specifically analysed whether treating mice at advanced ages with SS-31Â could reverse established markers of physical decline.
Glutathione & The Reversal of Age-Related Mitochondrial Decay
This human translational trial evaluated how correcting age-related glutathione deficiency impacts mitochondrial fuel burning, insulin resistance, and overall systemic fat oxidation.
The Effects of of NAD+ on the Reversal of Age-Related Mitochondrial Decay
This landmark preclinical study demonstrated that restoring NAD+ levels can completely reverse age-related mitochondrial dysfunction, effectively turning back the biological clock in mammalian tissues.
Immune Resilience Research
Neutralization of Endotoxins and Suppression of Cytokine Storms with LL-37
This foundational study demonstrates how LL-37 physically intercepts bacterial toxins to prevent a hyper-inflammatory response, effectively neutralising the triggers of immune collapse.
Geroprotective Efficacy of Thymalin Injections in Elderly Populations
This landmark, long-term human clinical trial evaluated the survival rates and immune parameters of advanced-age adults administered regular cycles of Thymalin over a multi-year monitoring period.
Dual Modulation of Innate and Adaptive Immunity with Thymosin Alpha-1 (Ta1)
This foundational molecular study maps out the precise cell-surface receptor pathways Thymosin Alpha-1 utilises to activate immune defence cells while keeping hyper-inflammation tightly in check.
Cognitive Function
Comparison of Selank Against Traditional Benzodiazepines
This human clinical study evaluated the therapeutic efficacy of Selank in patients diagnosed with Generalized Anxiety Disorder (GAD), comparing its performance head-to-head against the traditional benzodiazepine medication Phenazepam.
Reversal of Cognitive Defects and Synaptic Deficits with P21
This longitudinal evaluation tracked what happens when P21 is administered prior to the full accumulation of neurodegenerative plaques, assessing its ability to prevent cognitive and physical structural decay.
Peak Activation Velocities and TREK-1 Channel Inhibition with PE-22-28
This foundational mechanical study established the exact binding potency of PE-22-28, proving that it matches or outperforms standard antidepressants at a fraction of the molecular size.
Cellular Energy Research
Melanotan II Injection for Erectile Dysfunction Evaluation:
By linking the amino acid backbone into a ring structure via a lactam bridge, researchers drastically increased its structural rigidity. This compact, cyclical shape allows MT-2 to cross the Blood-Brain Barrier (BBB), triggering a non-selective activation profile across both peripheral skin receptors and central nervous system receptors.
Efficacy and Safety of Afamelanotide (Melanotan I) in Patients with Erythropoietic Protoporphyria
To prevent rapid enzymatic breakdown, molecular engineers substituted native Methionine with Norleucine (Nle) and replaced L-Phenylalanine with D-Phenylalanine.
Vasoactive Intestinal Peptide and Long-Lasting Pacing of Central Nervous System Circadian Activity
This neurological study tracks how VIP orchestrates the central biological clock, proving that it controls long-term electrical firing frequencies within the brain's primary pacing architecture.